Doctoral research

Dr Aridas completed a PhD in perinatal medicine at Monash University, awarded for work on protecting the newborn brain when a baby is deprived of oxygen around the time of birth. The programme examined how brain injury develops in the hours after birth, and tested three protective strategies: cooling, umbilical cord blood cells and melatonin.

The work was pre-clinical, carried out at The Ritchie Centre with neurobiologists, fetal physiologists, obstetricians, neonatologists, neurologists and radiologists, and supported by more than $1 million in funding from the NHMRC, the Bill and Melinda Gates Foundation and philanthropic sources. Its findings have since informed the design of human trials of melatonin for newborn encephalopathy.

Why this matters in practice

Research training changes how a clinician reads evidence. It means being able to look past a headline or a single study, weigh how reliable a finding actually is, and explain plainly what is known, what is uncertain and what that means for one particular pregnancy.

The subject matter is directly relevant to obstetric practice: fetal wellbeing, the timing of birth, and what happens to a baby who has a difficult birth. That background informs decisions about surveillance, timing and escalation, and it supports frank conversations after a birth that did not go as hoped.

Recommendations are explained with the strength of the evidence behind them, including where the evidence is genuinely unclear. A working interest in fetal surveillance, growth and the timing of birth, developed through both doctoral research and maternal–fetal medicine training. Ongoing involvement in registrar and medical student teaching, obstetric emergency training and clinical governance. Founder of Viventem, an app that brings a pregnancy’s investigations and timelines together across public and private providers.
Doctorate
PhD, perinatal medicine — Monash University. Thesis: “Protecting the newborn brain at birth”
Research centre
The Ritchie Centre, Hudson Institute of Medical Research & Monash University
Presentations
10 international and 12 national conference presentations
Selected awards
Award for Best Translational Research (PSANZ); Cerebral Palsy Best Research Award (Cerebral Palsy Alliance & PSANZ); Tania Gunn Memorial Prize (FNPS); FameLab Victorian State Winner and National Finalist
Publications

Peer-reviewed articles

Where a PubMed record exists, the citation links to it.

A complete and current list is maintained at ORCID 0000-0002-4000-2110.

Aridas JDS, Yawno T, Sutherland AE, et al. Journal of Pineal Research. 2021;71(1):e12744.
Aridas JDS, Yawno T, Sutherland AE, et al. Journal of Pineal Research. 2018;64(4):e12479.
Aridas JDS, McDonald CA, Paton MCB, et al. The Journal of Physiology. 2016;594(5):1421–1435.
Aridas JDS, Yawno T, Sutherland AE, et al. Experimental Neurology. 2014;261:281–290.
Sobotka KS, Morley C, Ong T, Polglase GR, Aridas JDS, et al. PLoS ONE. 2014;9(11):e112264.
Polglase GR, Miller SL, Barton SK, Baburamani AA, Wong FY, Aridas JDS, et al. PLoS ONE. 2012;7(6):e39535.
Crinall K, Ward M, McDonald R, Crinall W, Aridas J, Rolnik DL. Evaluation Journal of Australasia. 2022;22(2).

Selected first-author abstracts

Melatonin reduces inflammation-related brain injury in the newborn asphyxiated lamb. Journal of Paediatrics and Child Health, 2015.
Hypoxic brain injury in newborn lambs treated with hypothermia is further improved with melatonin combination therapy. Journal of Paediatrics and Child Health, 2014.
Potential of autologous umbilical cord blood for the early treatment of hypoxic brain injury. Journal of Paediatrics and Child Health, 2013.
Melatonin is a potential therapy for asphyxia-induced hypoxic-ischaemic encephalopathy in developing countries. International Congress of Paediatrics, 2013.
Melatonin protects the newborn lamb brain following an acute asphyxic insult at birth. Journal of Paediatrics and Child Health, 2012.
Media and public speaking

Talking about this work publicly

Research only helps families if it can be explained clearly. Dr Aridas has spoken about newborn brain injury and pregnancy care on television, radio and in print, and at events for both scientific and general audiences.

Coverage of the research

Hudson Institute of Medical Research
Monash Magazine, October 2014, pp. 26–29 — words by Melissa Marino (PDF)
Hudson Institute of Medical Research
Herald Sun — print (PDF)
Australian Science — feature article (PDF)

Broadcast interviews

Television interview
Nine News Brisbane
The Science Show with Robyn Williams
ABC Radio National, 18 August 2012
The Morning Show with Ellen Fanning
ABC Radio
Interview with Ella Archibald-Binge
SBS Radio
The Afternoon Show with Harvey Deegan
6PR

Clinical practice

ABC News online, 23 December 2022 — on delivering a baby with a giant omphalocele

Invited speaking

Invited scientific presentation
Melbourne Writers Festival
Invited speaker, district and national meetings
Inner Wheel Australia
Grand round, invited speaker
Monash Children’s Hospital
Invited speaker
Victorian Paediatric Rehabilitation Services

Media enquiries can be directed to the practice on the contact page.